Tuesday, April 21, 2026 Issue No. 047 Last Updated 14 Minutes Ago
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Issue No. 047 Tuesday, April 21, 2026 Vol. 3 · Weekly Edition
WellnessWire
1,247 Stories Published Since 2023 Health, With the Receipts.
Filing since January 2022
Senior Science Editor

Marcus Holt

Covers the next-generation molecules — retatrutide, survodutide, and anything with three or more receptor targets in the same injection.

Bylines on file
97
Filing since
January 2022
On the masthead
4 years
Filed from
Chicago, Illinois
Desks
Tirzepatide desk (lead)Peptides & Beyond (senior contributor)
Pronouns
he / him

Marcus writes about pharmacology from the perspective of a chemist who can read a protocol and a journalist who can read a room. He was at C&EN for four years before joining Wellness Wire in 2022.

He has spent the last eighteen months on the dual- and triple-agonist pipeline, and is currently finishing a book on the failed obesity drugs of the 1990s and what their failure taught us about the ones that worked.

If you want to know which molecule Eli Lilly is quietly running into Phase II next quarter, he is usually the last person in the newsroom to tell you, and the first one to be right when the press release drops.

Most of my beat is reading Phase II supplementary appendices at one in the morning and trying to figure out if the effect is the molecule or the crowd. — Holt, in conversation with the newsroom